The fifth conference ICNAS 2021 is a scientific event that brings together scientific expertise on several areas of scientific research. This biennial conference is the successor of the conference ICNAS 2013, ICNAS 2015, ICNAS 2017,and ICNAS 2019. In fact, the areas of interest ICNAS 2021 are valid with a cross between different research themes. Through this conference, the scientific frontiers are pushed and multidisciplinary investigations allow researchers and young researchers to propose their ideas and contributions. The conference deals with topics relating to networking, management, and systems that revolve around this technology. The systems are advanced systems by their design, implementation, and applications.